Open access

987 Glioma-derived factors induce an immune suppressive phenotype in bone marrow-derived CCR2+ myeloid cells
Gregory Takacs, Julia Garcia, Alexandra Sherman, Christian Kreiger, Defang Luo, Jeffrey Harrison

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1094; DOI: 10.1136/jitc-2023-SITC2023.0987
988 Vagal-CD8+ T cell neuroimmune axis modulates liver cancer
Kylynda C Bauer, Benjamin Ruf, Yuta Myojin, Mohamed-Reda Benmebarek, Chi Ma, Amran Nur, Jonathan Qi, Benjamin L Green, Simon Wabitsch, Rajiv Trehan, Danielle Springer, Audrey Noguchi, Morteza Peiravi, Heather Potts, Firouzeh Korangy, Tim F Greten

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1095; DOI: 10.1136/jitc-2023-SITC2023.0988
989 Cancer sculpts granulopoiesis to generate tumor-supportive neutrophils
Andres Hidalgo, Daniela C Cerezo-Wallis

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1096; DOI: 10.1136/jitc-2023-SITC2023.0989
990 Context dependent effects of TIGIT expression on circulating versus intratumoral NK and CD8 T cells in mouse and human sarcoma models
Marshall Lammers, Cyrus Sholevar, Sean Judge, Sylvia Cruz, Lauren Farley, Khurshid Iranpur, Ryan Nielsen, Aryana Razmara, Arta Monjazeb, William Murphy, Robert Canter

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1097; DOI: 10.1136/jitc-2023-SITC2023.0990
991 Effects of SAR443579, a trifunctional anti-CD123 NK cell engager (NKCE), on natural killer (NK) cell subsets at the single cell level
Galina Boldina, Manoel Nunes, Karine Berthelot, Wilson Dos-Santos-Bele, Fabien Delahaye, Franck Augé, Angelique Biancotto, Angela Hadjipanayis, Matteo Cesaroni, Angela Virone-Oddos, Donald Jackson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1098; DOI: 10.1136/jitc-2023-SITC2023.0991
992 Immunomodulatory nature of glioblastoma-derived lipids against human NKT cells
Morgan Coombs, Tyrone Dowdy, Masud Alam, Guzal Khayrullina, Vibhuti Joshi, Seketoulie Keretsu, Jinkyu Jung, Ayaka Hara, Kelsey Smith, Jenny Gumperz, Mioara Larion, Masaki Terabe

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1099; DOI: 10.1136/jitc-2023-SITC2023.0992
993 Knockout of DNAM-1 competing inhibitory receptors enhances natural killer cell anti-tumor functions against neuroblastoma
Tayler J Croom-Perez, Liza D Robles-Carrillo, Jeremiah L Oyer, Faqrul Hasan, Sanjana Kumar, Brendan W Andersen, Javier A Rivera-Huertas, Brian P Tullius, Alicja J Copik

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1100; DOI: 10.1136/jitc-2023-SITC2023.0993
994 Functional assays on the single cell level: advantages and applications for NK killing assays
Nora Fekete-Drimusz, Alessia Dunst, Bas Lievaart, Jannis Naehring, Robin Krüger

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1101; DOI: 10.1136/jitc-2023-SITC2023.0994
995 Modulation of the inflammatory response within the tumor microenvironment by intraepithelial ILC1-like natural killer cells
Sainiteesh Maddineni, Imran A Mohammad, Krishna Sharma, JuneHo Shin, John B Sunwoo

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1102; DOI: 10.1136/jitc-2023-SITC2023.0995
996 Studies of newly discovered adaptive NK cells in CMV-related tumors
Nerea Martin Almazan, Dhifaf Sarhan

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1103-A1104; DOI: 10.1136/jitc-2023-SITC2023.0996

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