Journal for ImmunoTherapy of Cancer

Changes in circulating tumor DNA and outcomes in solid tumors treated with immune checkpoint inhibitors: a systematic review
Laith Al-Showbaki, Brooke Wilson, Faris Tamimi, Consolacion Molto, Abhenil Mittal, David W Cescon, Eitan Amir

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005854; DOI: 10.1136/jitc-2022-005854
BRCA1 deficiency in mature CD8⁺ T lymphocytes impairs antitumor immunity
Bogang Wu, Leilei Qi, Huai-Chin Chiang, Haihui Pan, Xiaowen Zhang, Alexandra Greenbaum, Elizabeth Stark, Li-Ju Wang, Yidong Chen, Bassem R. Haddad, Dionyssia Clagett, Claudine Isaacs, Richard Elledge, Anelia Horvath, Yanfen Hu, Rong Li

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005852; DOI: 10.1136/jitc-2022-005852
Senescent cancer cell vaccines induce cytotoxic T cell responses targeting primary tumors and disseminated tumor cells
Yue Liu, Joanna Pagacz, Donald J Wolfgeher, Kenneth D Bromerg, Jacob V Gorman, Stephen J Kron

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005862; DOI: 10.1136/jitc-2022-005862
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Esther Schoutrop, Thomas Poiret, Ibrahim El-Serafi, Ying Zhao, Rui He, Alina Moter, Johan Henriksson, Moustapha Hassan, Isabelle Magalhaes, Jonas Mattsson

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005691; DOI: 10.1136/jitc-2022-005691
CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden
Jitske van den Bulk, Manon van der Ploeg, Marieke E Ijsselsteijn, Dina Ruano, Ruud van der Breggen, Rebekka Duhen, Koen C M J Peeters, Arantza Fariña-Sarasqueta, Els M E Verdegaal, Sjoerd H van der Burg, Thomas Duhen, Noel F C C de Miranda

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005887; DOI: 10.1136/jitc-2022-005887
Phase 1 first-in-human study of dalutrafusp alfa, an anti–CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors
Anthony W Tolcher, Michael Gordon, Kathleen M Mahoney, Anna Seto, Marianna Zavodovskaya, Chia-Hsiang Hsueh, Shuyan Zhai, Thomas Tarnowski, Juliane M Jürgensmeier, Susanna Stinson, Ahmed A Othman, Tianling Chen, James Strauss

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005267; DOI: 10.1136/jitc-2022-005267
Runx3-overexpression cooperates with ex vivo AKT inhibition to generate receptor-engineered T cells with better persistence, tumor-residency, and antitumor ability
Jianghui Tang, Jianpeng Sheng, Qi Zhang, Yongtao Ji, Xun Wang, Junlei Zhang, Jiangchao Wu, Jinyuan Song, Xueli Bai, Tingbo Liang

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006119; DOI: 10.1136/jitc-2022-006119
COVID-19 vaccination in patients with cancer receiving immune checkpoint inhibitors: a systematic review and meta-analysis
Juan Ignacio Ruiz, Maria Angeles Lopez-Olivo, Yimin Geng, Maria E Suarez-Almazor

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006246; DOI: 10.1136/jitc-2022-006246
PKR induces TGF-β and limits oncolytic immune therapy
Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Guangsheng Pei, Yuanqing Yan, Yoshihiro Otani, Yeshavanth Banasavadi-Siddegowda, Huihui Fan, Zhongming Zhao, Jianhua Yu, Michael A Caligiuri, Balveen Kaur

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006164; DOI: 10.1136/jitc-2022-006164
PD-L1 gene amplification and focality: relationship with protein expression
Denis Leonardo Jardim, Karthikeyan Murugesan, Julia A. Elvin, Richard S. P. Huang, Razelle Kurzrock

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006311; DOI: 10.1136/jitc-2022-006311

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