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BMJ Journals
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Journal for ImmunoTherapy of Cancer
Journal for ImmunoTherapy of Cancer
281 Development of syngeneic mouse models to study the therapeutic efficacy of chimeric antigen receptor T cells against solid tumors
Ping-Hsien
Lee
,
Shannon
Breen
,
Ashley
Merlino
,
Lorenzo
Ortiz
,
Rosa
Carrasco
,
Gordon
Moody
,
Allison
Barrett
,
Letizia
Giardino
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A322;
DOI:
10.1136/jitc-2023-SITC2023.0281
282 Dual antigen targeting CAR T cells armored with a dominant-negative TGF-β Receptor II enhance antitumor potency by overcoming TGF-β immunosuppression in GBM
Nannan
Li
,
Jesse
Rodriguez
,
Zev
Binder
,
Donald
O’Rourke
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A323;
DOI:
10.1136/jitc-2023-SITC2023.0282
283 Preclinical development and characterization of allogeneic CAR T cells targeting Claudin18.2-positive tumors
Zhe
Li
,
Barbra
Sasu
,
Siler
Panowski
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A324;
DOI:
10.1136/jitc-2023-SITC2023.0283
284 A novel hybrid T-cell receptor form of CAR-T cells showed enhanced activity against solid tumors
Meiou
Liu
,
Yasushi
Akahori
,
Hiroshi
Fujiwara
,
Yoshihiro
Miyahara
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A325;
DOI:
10.1136/jitc-2023-SITC2023.0284
285 Proof-of-concept of a non-gene editing technology using shRNA down-regulation to engineer and optimize CAR T-cell functionality
Caroline
Lonez
,
Jennifer
Bolsee
,
Fanny
Huberty
,
Thuy
Nguyen
,
Celine
Jacques-Hespel
,
Benjamin
Demoulin
,
Anne
Flament
,
Eytan
Breman
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A326;
DOI:
10.1136/jitc-2023-SITC2023.0285
286 Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
Leyuan
Ma
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A327-A328;
DOI:
10.1136/jitc-2023-SITC2023.0286
287 Identification of potentially safe and selective CAR targets for head and neck cancer via a pan-cancer single cell transcriptome analysis
Sanna
Madan
,
Eytan
Ruppin
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A329;
DOI:
10.1136/jitc-2023-SITC2023.0287
289 Defining the T cell functional attributes of effective CAR T cell donors
Michaela
Meehl
,
Meghan W
Dukes
,
Giedre
Krenciute
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A330;
DOI:
10.1136/jitc-2023-SITC2023.0289
290 IL-15 is required for optimal anti-tumor activity of Vγ9Vδ2 T cells against glioblastoma
Allyson E
Moore
,
Nickolas
Serniuck
,
Arya
Afsahi
,
Hayley
Nault
,
Sheila K
Singh
,
Jonathan L
Bramson
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A331;
DOI:
10.1136/jitc-2023-SITC2023.0290
291 Time-resolved analysis of CAR-T cell induced apoptosis of low frequency target cells using an Image-enhanced flow cytometer was enabled by fluorescent protein compensation with BrightComp eBeads
Jayanth S
Narayanan
,
Erin
Taylor
Journal for ImmunoTherapy of Cancer
Nov 2023,
11
(Suppl 1)
A332;
DOI:
10.1136/jitc-2023-SITC2023.0291
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