JITC

Risk of tuberculosis in patients with cancer treated with immune checkpoint inhibitors: a nationwide observational study
Seongman Bae, Ye-Jee Kim, Min-ju Kim, Jwa Hoon Kim, Sung-Cheol Yun, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sung-Han Kim, Sang-Ho Choi, Yang Soo Kim, Sang-Oh Lee

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002960; DOI: 10.1136/jitc-2021-002960
Immune cell and tumor cell-derived CXCL10 is indicative of immunotherapy response in metastatic melanoma
Robin Reschke, Jovian Yu, Blake A Flood, Emily F Higgs, Ken Hatogai, Thomas F Gajewski

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003521; DOI: 10.1136/jitc-2021-003521
Activated osteoarthritis following immune checkpoint inhibitor treatment: an observational study
Pankti Reid, David FL Liew, Rajshi Akruwala, Anne R Bass, Karmela K Chan

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003260; DOI: 10.1136/jitc-2021-003260
Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy.
David J. Pinato, Sam M Murray, Alejandro Forner, Takahiro Kaneko, Petros Fessas, Pierluigi Toniutto, Beatriz Mínguez, Valentina Cacciato, Claudio Avellini, Alba Diaz, Rosemary J. Boyton, Daniel M. Altmann, Robert D Goldin, Ayse U Akarca, Teresa Marafioti, Francesco A Mauri, Edoardo Casagrande, Federica Grillo, Edoardo Giannini, Sherrie Bhoori, Vincenzo Mazzaferro

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003311; DOI: 10.1136/jitc-2021-003311
Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design
Haiying Qin, Lila Yang, John A Chukinas, Nirali N Shah, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Naomi A Taylor, Sarah K Tasian, Terry J Fry

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003149; DOI: 10.1136/jitc-2021-003149
Loss of host tissue transglutaminase boosts antitumor T cell immunity by altering STAT1/STAT3 phosphorylation in ovarian cancer
Livia Elena Sima, Siqi Chen, Horacio Cardenas, Guangyuan Zhao, Yinu Wang, Cristina Ivan, Hao Huang, Bin Zhang, Daniela Matei

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002682; DOI: 10.1136/jitc-2021-002682
High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4⁺ and CD8⁺ neoantigen-specific T cells to promote antitumor immunity
Rosmely Hernandez, Kathryn M LaPorte, Sunnie Hsiung, Alicia Santos Savio, Thomas R Malek

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002865; DOI: 10.1136/jitc-2021-002865
Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Masaaki Komatsu, Hirokazu Matsushita, Kazuhiro Kakimi, Eiryo Kawakami, Katsuyuki Shiroguchi, Heiichiro Udono

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002954; DOI: 10.1136/jitc-2021-002954
CD8⁺ TILs in NSCLC differentiate into TEMRA via a bifurcated trajectory: deciphering immunogenicity of tumor antigens
Sung-Woo Lee, He Yun Choi, Gil-Woo Lee, Therasa Kim, Hyun-Ju Cho, In-Jae Oh, Sang Yun Song, Deok Hwan Yang, Jae-Ho Cho

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002709; DOI: 10.1136/jitc-2021-002709
Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy
James McAuliffe, Hok Fung Chan, Laurine Noblecourt, Ramiro Andrei Ramirez-Valdez, Vinnycius Pereira-Almeida, Yaxuan Zhou, Emily Pollock, Federica Cappuccini, Irina Redchenko, Adrian VS Hill, Carol Sze Ki Leung, Benoit J Van den Eynde

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003218; DOI: 10.1136/jitc-2021-003218

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