JITC

Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model
Zhenqiang Sun, Yanxin Xu, Bo Shao, Pengyuan Dang, Shengyun Hu, Haifeng Sun, Chen Chen, Chaoguan Wang, Jinbo Liu, Yang Liu, Junhong Hu

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008491; DOI: 10.1136/jitc-2023-008491
Developing a membrane-proximal CD33-targeting CAR T cell
Ruby Freeman, Sanam Shahid, Abdul G Khan, Serena C Mathew, Sydney Souness, Erin R Burns, Jasmine S Um, Kento Tanaka, Winson Cai, Sarah Yoo, Andrew Dunbar, Young Park, Devin McAvoy, Kinga K Hosszu, Ross L Levine, Jaap Jan Boelens, Ivo C Lorenz, Renier J Brentjens, Anthony F Daniyan

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e009013; DOI: 10.1136/jitc-2024-009013
Sequence of androgen receptor-targeted vaccination with androgen deprivation therapy affects anti-prostate tumor efficacy
Anusha Muralidhar, Melissa Gamat-Huber, Sita Vakkalanka, Douglas G McNeel

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008848; DOI: 10.1136/jitc-2024-008848
Comprehensive profiling of cancer neoantigens from aberrant RNA splicing
Daniel P Wickland, Colton McNinch, Erik Jessen, Brian Necela, Barath Shreeder, Yi Lin, Keith L Knutson, Yan W Asmann

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008988; DOI: 10.1136/jitc-2024-008988
Safety and biological outcomes following a phase 1 trial of GD2-specific CAR-T cells in patients with GD2-positive metastatic melanoma and other solid cancers
Tessa Gargett, Nga T H Truong, Bryan Gardam, Wenbo Yu, Lisa M Ebert, Amy Johnson, Erica C F Yeo, Nicole L Wittwer, Gonzalo Tapia Rico, Jesikah Logan, Purany Sivaloganathan, Maria Collis, Andrew Ruszkiewicz, Michael P Brown

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008659; DOI: 10.1136/jitc-2023-008659
Therapeutic Inducers of Natural Killer cell Killing (ThINKK): preclinical assessment of safety and efficacy in allogeneic hematopoietic stem cell transplant settings
Nicolas Poirier, Valérie Paquin, Séverine Leclerc, Véronique Lisi, Carolina Marmolejo, Hicham Affia, Paulo Cordeiro, Yves Théorêt, Elie Haddad, Gregor Andelfinger, Vincent Philippe Lavallée, Michel Duval, Sabine Herblot

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008435; DOI: 10.1136/jitc-2023-008435
Colorectal cancer-specific IFNβ delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy
Kevin Chih-Yang Huang, Shu-Fen Chiang, Hsin-Yu Chang, Wei-Ze Hong, Jhen-Yu Chen, Pei-Chih Lee, Ji-An Liang, Tao-Wei Ke, Shin-Lei Peng, An‑Cheng Shiau, Tsung-Wei Chen, Pei-Chen Yang, William Tzu-Liang Chen, K S Clifford Chao

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008515; DOI: 10.1136/jitc-2023-008515
Development and interpretation of a pathomics-driven ensemble model for predicting the response to immunotherapy in gastric cancer
Zhen Han, Zhicheng Zhang, Xianqi Yang, Zhe Li, Shengtian Sang, Md Tauhidul Islam, Alyssa A Guo, Zihan Li, Xiaoyan Wang, Jing Wang, Taojun Zhang, Zepang Sun, Lequan Yu, Wei Wang, Wenjun Xiong, Guoxin Li, Yuming Jiang

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008927; DOI: 10.1136/jitc-2024-008927
Stealth transgenes enable CAR-T cells to evade host immune responses
Korneel Grauwet, Trisha Berger, Michael C Kann, Harrison Silva, Rebecca Larson, Mark B Leick, Stefanie R Bailey, Amanda A Bouffard, David Millar, Kathleen Gallagher, Cameron J Turtle, Matthew J Frigault, Marcela V Maus

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008417; DOI: 10.1136/jitc-2023-008417
Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells
Richard Baugh, Hena Khalique, Emma Page, Janet Lei-Rossmann, Peter Kok-Ting Wan, Timothy Johanssen, Daniel Ebner, Olaf Ansorge, Leonard W Seymour

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008460; DOI: 10.1136/jitc-2023-008460

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