Immunotherapy Biomarkers

Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment
Yuxuan Song, Yun Peng, Caipeng Qin, Yulong Wang, Wenbo Yang, Yiqing Du, Tao Xu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006643; DOI: 10.1136/jitc-2022-006643
Hsa-LINC02418/mmu-4930573I07Rik regulated by METTL3 dictates anti-PD-L1 immunotherapeutic efficacy via enhancement of Trim21-mediated PD-L1 ubiquitination
Zhijia Sun, Haixing Mai, Chunyuan Xue, Zhongyi Fan, Jiangbo Li, Hairui Chen, Nan Huo, Xiaofeng Kang, Chuanhao Tang, Liaoxin Fang, Hui Zhao, Yuchen Han, Chao Sun, Huanyan Peng, Yimeng Du, Jing Yang, Nan Du, Xiaojie Xu

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007415; DOI: 10.1136/jitc-2023-007415
Targeting integrin α5 in fibroblasts potentiates colorectal cancer response to PD-L1 blockade by affecting extracellular-matrix deposition
Ling Lu, Yaohui Gao, Dengfeng Huang, Hu Liu, Dingzi Yin, Man Li, Jiayi Zheng, Shufei Wang, Weijun Wu, Li Zhao, Dexi Bi, Youhua Zhang, Feifei Song, Ruting Xie, Jifeng Wang, Huanlong Qin, Qing Wei

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007447; DOI: 10.1136/jitc-2023-007447
Heterogeneity in tertiary lymphoid structures predicts distinct prognosis and immune microenvironment characterizations of clear cell renal cell carcinoma
Wenhao Xu, Jiahe Lu, Wang-Rui Liu, Aihetaimujiang Anwaier, Yuhao Wu, Xi Tian, Jia-Qi Su, Yuan-Yuan Qu, Jianfeng Yang, Hailiang Zhang, Dingwei Ye

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e006667; DOI: 10.1136/jitc-2023-006667
Evaluation of tissue- and plasma-derived tumor mutational burden (TMB) and genomic alterations of interest in CheckMate 848, a study of nivolumab combined with ipilimumab and nivolumab alone in patients with advanced or metastatic solid tumors with high TMB
Jie He, Natallia Kalinava, Parul Doshi, Dean C Pavlick, Lee A Albacker, Ericka M Ebot, Hanna Tukachinsky, James Pratt, Gina Fusaro, Geoffrey R Oxnard, George Green, David Fabrizio, Jonathan Baden

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007339; DOI: 10.1136/jitc-2023-007339
Assessment and predictive ability of the absolute neutrophil count in peripheral blood for in vivo CAR T cells expansion and CRS
Man Zhang, Xiaolu Long, Yi Xiao, Jin Jin, Caixia Chen, Jiao Meng, Wanying Liu, Aichun Liu, Liting Chen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007790; DOI: 10.1136/jitc-2023-007790
Biologic subtypes of melanoma predict survival benefit of combination anti-PD1+anti-CTLA4 immune checkpoint inhibitors versus anti-PD1 monotherapy
April A N Rose, Susan M Armstrong, David Hogg, Marcus O Butler, Samuel D Saibil, Diana P Arteaga, Thiago Pimentel Muniz, Deirdre Kelly, Danny Ghazarian, Ian King, Zaid Saeed Kamil, Kendra Ross, Anna Spreafico

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001642; DOI: 10.1136/jitc-2020-001642
Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression
Marina Natoli, John Gallon, Haonan Lu, Ala Amgheib, David J Pinato, Francesco A Mauri, Teresa Marafioti, Ayse U Akarca, Ines Ullmo, Jacey Ip, Eric O Aboagye, Robert Brown, Anastasios Karadimitris, Sadaf Ghaem-Maghami

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001519; DOI: 10.1136/jitc-2020-001519
CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
Moran Yang, Jiaqi Lu, Guodong Zhang, Yiying Wang, Mengdi He, Qing Xu, Congjian Xu, Haiou Liu

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001136; DOI: 10.1136/jitc-2020-001136
Non-invasive CT imaging biomarker to predict immunotherapy response in gastric cancer: a multicenter study
Weicai Huang, Wenjun Xiong, Lei Tang, Chuanli Chen, Qingyu Yuan, Cheng Zhang, Kangneng Zhou, Zepang Sun, Taojun Zhang, Zhen Han, Hao Feng, Xiaokun Liang, Yonghong Zhong, Haijun Deng, Lequan Yu, Yikai Xu, Wei Wang, Lin Shen, Guoxin Li, Yuming Jiang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007807; DOI: 10.1136/jitc-2023-007807

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