Immunotherapy Biomarkers

High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC)
Myrto K Moutafi, Katherine M Bates, Thazin Nwe Aung, Rolando Garcia Milian, Vasiliki Xirou, Ioannis A Vathiotis, Niki Gavrielatou, Athanasios Angelakis, Kurt A Schalper, Leonidas Salichos, David L Rimm

Journal for ImmunoTherapy of Cancer Jun 2024, 12 (6) e009039; DOI: 10.1136/jitc-2024-009039
Characterizations of multi-kingdom gut microbiota in immune checkpoint inhibitor-treated hepatocellular carcinoma
Chengpei Zhu, Chenchen Zhang, Shanshan Wang, Ziyu Xun, Dongya Zhang, Zhou Lan, Longhao Zhang, Jiashuo Chao, Yajun Liang, Zilun Pu, Cong Ning, Xinting Sang, Xiaobo Yang, Hanping Wang, Xianzhi Jiang, Haitao Zhao

Journal for ImmunoTherapy of Cancer Jun 2024, 12 (6) e008686; DOI: 10.1136/jitc-2023-008686
Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities
Alvaro Lopez Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano, Alvaro Teijeira, Kurt A Schalper, Ignacio Melero, Carlos E De Andrea

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008589; DOI: 10.1136/jitc-2023-008589
Interactions between LAMP3+ dendritic cells and T-cell subpopulations promote immune evasion in papillary thyroid carcinoma
Zhiyuan Wang, Xiaoyu Ji, Ye Zhang, Fan Yang, Hongyue Su, Hao Zhang, Zhendong Li, Wenqian Zhang, Wei Sun

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008983; DOI: 10.1136/jitc-2024-008983
Comprehensive profiling of cancer neoantigens from aberrant RNA splicing
Daniel P Wickland, Colton McNinch, Erik Jessen, Brian Necela, Barath Shreeder, Yi Lin, Keith L Knutson, Yan W Asmann

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008988; DOI: 10.1136/jitc-2024-008988
Development and interpretation of a pathomics-driven ensemble model for predicting the response to immunotherapy in gastric cancer
Zhen Han, Zhicheng Zhang, Xianqi Yang, Zhe Li, Shengtian Sang, Md Tauhidul Islam, Alyssa A Guo, Zihan Li, Xiaoyan Wang, Jing Wang, Taojun Zhang, Zepang Sun, Lequan Yu, Wei Wang, Wenjun Xiong, Guoxin Li, Yuming Jiang

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008927; DOI: 10.1136/jitc-2024-008927
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs
Gan Xiong, Zhi Chen, Qianwen Liu, Fang Peng, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Shuang Chen, Yu Liang, Demeng Chen, Qimin Zhou

Journal for ImmunoTherapy of Cancer May 2024, 12 (5) e008662; DOI: 10.1136/jitc-2023-008662
Interferon-gamma signature as prognostic and predictive marker in macroscopic stage III melanoma
Judith M Versluis, Stephanie A Blankenstein, Petros Dimitriadis, James S Wilmott, Robert Elens, Willeke A M Blokx, Winan van Houdt, Alexander Maxwell Menzies, Yvonne M Schrage, Michel W J M Wouters, Joyce Sanders, Annegien Broeks, Richard A Scolyer, Karijn P M Suijkerbuijk, Georgina V Long, Alexander C J van Akkooi, Christian U Blank

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e008125; DOI: 10.1136/jitc-2023-008125
Total metabolic tumor volume on ¹⁸F-FDG PET/CT is a game-changer for patients with metastatic lung cancer treated with immunotherapy
Pierre Tricarico, David Chardin, Nicolas Martin, Sara Contu, Florent Hugonnet, Josiane Otto, Olivier Humbert

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e007628; DOI: 10.1136/jitc-2023-007628
Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+T cells in the tumor microenvironment and predicts clinical outcome in early-phase and late-phase clinical trials
Andreas Roller, Iakov I Davydov, Petra C Schwalie, Martha L Serrano-Serrano, Astrid Heller, Nicolas Staedler, Cláudia S Ferreira, Gabriele Dietmann, Irina Klaman, Alberto Valdeolivas, Konstanty Korski, Michael A Cannarile

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e008185; DOI: 10.1136/jitc-2023-008185

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