Immune Cell Therapies and Immune Cell Engineering

Dual oxidase 1 limits the IFNγ-associated antitumor effect of macrophages
Lydia Meziani, Marine Gerbé de Thoré, Pauline Hamon, Sophie Bockel, Ruy A Louzada, Céline Clemenson, Raphaël Corre, Winchygn Liu, Corinne Dupuy, Michele Mondini, Eric Deutsch

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000622; DOI: 10.1136/jitc-2020-000622
Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer
Saisha A Nalawade, Paul Shafer, Pradip Bajgain, Mary K McKenna, Arushana Ali, Lauren Kelly, Jarrett Joubert, Stephen Gottschalk, Norihiro Watanabe, Ann Leen, Robin Parihar, Juan Fernando Vera Valdes, Valentina Hoyos

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003237; DOI: 10.1136/jitc-2021-003237
Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants
Enrique Conde, Enric Vercher, Marta Soria-Castellano, Jesús Suarez-Olmos, Uxua Mancheño, Edurne Elizalde, M Luis Rodriguez, Javier Glez-Vaz, Noelia Casares, Estefanía Rodríguez-García, Mirja Hommel, Gloria González-Aseguinolaza, Iratxe Uranga-Murillo, Julian Pardo, Gorka Alkorta, Ignacio Melero, Juan Lasarte, Sandra Hervas-Stubbs

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003351; DOI: 10.1136/jitc-2021-003351
'Off-the-shelf’ allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies
Debottam Sinha, Sriganesh Srihari, Kirrliee Beckett, Laetitia Le Texier, Matthew Solomon, Archana Panikkar, George R Ambalathingal, Lea Lekieffre, Pauline Crooks, Sweera Rehan, Michelle A. Neller, Corey Smith, Rajiv Khanna

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001608; DOI: 10.1136/jitc-2020-001608
Chemical priming of natural killer cells with branched polyethylenimine for cancer immunotherapy
Seung Hee Choi, Hye Jin Kim, Joo Dong Park, Eun-Su Ko, Minwook Lee, Dae-Keum Lee, Jin-Ho Choi, Hye Jung Jang, Isaac Kim, Hae-Yun Jung, Keun-Hong Park, Kyung-Soon Park

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e004964; DOI: 10.1136/jitc-2022-004964
Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Celia Martín-Otal, Aritz Lasarte-Cia, Diego Serrano, Noelia Casares, Enrique Conde, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, Alfonso Calvo, Carlos E De Andrea, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel, Felipe Prosper, Sandra Hervas-Stubbs, Juan Jose Lasarte, Teresa Lozano

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e004479; DOI: 10.1136/jitc-2021-004479
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding
Evripidis Lanitis, Paris Kosti, Catherine Ronet, Elisabetta Cribioli, Giorgia Rota, Aodrenn Spill, Patrick Reichenbach, Vincent Zoete, Denarda Dangaj Laniti, George Coukos, Melita Irving

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002151; DOI: 10.1136/jitc-2020-002151
NK cells enhance CAR-T cell antitumor efficacy by enhancing immune/tumor cells cluster formation and improving CAR-T cell fitness
Mireia Bachiller, Lorena Perez-Amill, Anthony Matthew Battram, Sebastian Ciro Carné, Amer Najjar, Els Verhoeyen, Manel Juan, Alvaro Urbano-Ispizua, Beatriz Martin-Antonio

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002866; DOI: 10.1136/jitc-2021-002866
Induction of EBV latent membrane protein-2A (LMP2A)-specific T cells and construction of individualized TCR-engineered T cells for EBV-associated malignancies
Chaoting Zhang, Qin Tan, Shance Li, Luyan Shen, Jingtao Zhang, Ying Liu, Wenjun Yang, Zheming Lu

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002516; DOI: 10.1136/jitc-2021-002516
Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma
Troels Holz Borch, Katja Harbst, Aynal Haque Rana, Rikke Andersen, Evelina Martinenaite, Per Kongsted, Magnus Pedersen, Morten Nielsen, Julie Westerlin Kjeldsen, Anders Handrup Kverneland, Martin Lauss, Lisbet Rosenkrantz Hölmich, Helle Hendel, Özcan Met, Göran Jönsson, Marco Donia, Inge Marie Svane

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002703; DOI: 10.1136/jitc-2021-002703

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